Description
Seretide 25/50Mcgmdi
Description : 100 Diskus Salmeterol xinafoate 50 mcg, fluticasone propionate 100 mcg. 250 Diskus Salmeterol xinafoate 50 mcg, fluticasone propionate 250 mcg. 500 Diskus Salmeterol xinafoate 50 mcg, fluticasone propionate 500 mcg. 25/50 MDI Salmeterol xinafoate 25 mcg, fluticasone propionate 50 mcg. 25/125 MDI Salmeterol xinafoate 25 mcg, fluticasone propionate 125 mcg. 25/250 MDI Salmeterol xinafoate 25 mcg, fluticasone propionate 250 mcg.
Indications / Uses : Regular treatment of reversible obstructive airways disease (ROAD) including asthma where use of combination therapy (bronchodilator & inhaled corticosteroid) is appropriate; COPD including chronic bronchitis & emphysema.
Contraindications : History of hypersensitivity to salmeterol, fluticasone propionate or any of the ingredients of Seretide.
Special Precautions : Not for relief of acute asthma symptoms. Consider increasing corticosteroid therapy in sudden & progressive deterioration of asthma control. Avoid abrupt w/drawal. Possible development of pneumonia in patients w/ COPD. Active or quiescent pulmonary TB, thyrotoxicosis, preexisting CV disease. Patients predisposed to low serum K levels. Systemic effects may occur at high doses for prolonged periods. Monitor height of childn receiving prolonged treatment. Possibility of impaired adrenal response in patients transferring from oral steroid therapy. History of DM. Concomitant use w/ ritonavir, ketoconazole & other strong CYP3A4 inhibitors. Discontinue use if paradoxical bronchospasm occurs. Pregnancy & lactation. Childn <4 yr.
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